UCLA Morphology of Cells & Retinoblastoma Discussion & Case Study

Description

Part 1: Discuss Morphology of cells and the factor it plays in general function and structure. Also, choose a condition from the following case studies: ventricular hypertrophy, Retinoblastoma, ADHD, Poisoning

Part 2 Select a topic and discuss the difference between various cells and the role these cells play in specific disease processes.

CASE STUDY:

A 2 two year old male presents with a retinal tumor and ultimately Retinoblastoma.

What is retinoblastoma, and what is the pattern of inheritance for this type of cancer?
What type of gene is the retinoblastoma gene, and how does mutation in this gene give rise to cancer? Be sure to indicate the consequences of mutating one or both of the alleles for this gene.
What is the difference between a germline and a somatic mutation?
What is the normal function of the pRB protein with regard to cell cycle regulation?

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