An Examination of the Relative Need for Genetic and Environmental Elements in Aetiology of Schizophrenia

An Evaluation of the Relative Need for Genetic and Environmental Elements in Aetiology of Schizophrenia

the relative need for genetic and environmental elements in the

aetiology of schizophrenia.

Graeme Gordon

.poor Ophelia, divided from herself and her good judgement without the which we arepictures or mere beasts.

Shakespeare, Hamlet

The term 'schizophrenia' (a splitting of psychic function, Strange, 1992) was first introduced in 1911 by Eugen Bleuler to denote the break down of integration between feelings, thought and activities. The symptoms of this disease will be heterogeneous and there continues to be disagreement about diagnosis.

The annual incidence of schizophrenia can be between 0.1 and 0.5 per 1000 depending on the diagnostic conditions used - representing an eternity risk of 1 % (Strange, 1992). Starting point of the condition is mostly in late adolescence or early on adulthood. In the U.S.A., schizophrenia fills more beds than nearly every other disease and the financial cost of schizophrenia because of direct

medical costs, lost productivity and Social Protection pensions is between $30 billion and $48 billion according

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